Description 
Nobilis RT +IB multi + G + ND is a combined inactivated vaccine for the active immunization of chickens against Infectious Bronchitis (serotype Massachusetts and D207 (strain D274 and related strains)) and against Newcastle Disease, Infectious Bursal Disease and Avian Rhinotracheitis.

Composition 
Active components

• Inactivated IB strain M41.
• Inactivated IB virus D 274. 
• Inactivated ART strain BUT 1 # 8544. 
• Inactivated IBD strain D78. 
• Inactivated ND strain Clone 30.

Formulation 
Water-in-oil emulsion.

Indications 
The vaccine is recommended for the booster vaccination of breeding stock against the Massachusetts and D207and related serotypes of Infectious Bronchitis, against Newcastle Disease, against the adverse effects of infection with Avian Rhinotracheitis, and to produce maternal antibodies in their progeny to protect against Gumboro Disease for at least the first few weeks of life.

Vaccination 
Nobilis RT + IB multi + ND + G should be given to birds not less than 4 weeks before the expected onset of lay. For an optimal booster effect, the birds must be primed with live vaccine against infectious Bronchitis, Avian Rhinotracheitis, Newcastle Disease and Infectious Bursal Disease. The best results will be obtained if vaccination with inactivated vaccine takes place 6 or more weeks after administration of the live primer but in no circumstances should it be carried out earlier than 4 weeks after priming.

Dosage 
Each bird: 0.5 ml.

Method of administration 
Intramuscularly in the thigh or breast muscle or subcutaneously in the lower part of the neck.

Withholding period 
None

Presentation 
500 ml (1000 doses) bottles.

Storage 
Store at a temperature of  2-8°C and avoid freezing.

Contra-indications 
When used according to instructions: None.

Further information 
Dispose of empty or part-used vials in accordance with local regulations.

Precautions

• Vaccinate healthy birds only. 
• Before use allow the vaccine to reach room temperature (20-25°C). 
• Shake the bottle well before use. 
• Use sterile injection equipment. 
• Use the entire contents when first opened. 
• Opened vials should be used within three hours. 
• Do not mix with other vaccines. 
• Should a vaccinator inject himself or a bystander by accident, a local reaction may occur. It is recommended that the advice of a doctor is sought, taking care to inform the doctor that the vaccine is an oil emulsion.